Which one is better and which one do you prefer?
I like Pokeroffice (and that's the one I use) because of the built in table overlay and the icons shown. I'm not very familiar with these programs so I don't know the differences between these two.
And I read that Holdem Manager will be even better than PT and PO. It will have everything the other 2 have and more.
http://www.holdemmanager.net/